Treatment of myelofibrosis and primary erythermalgia

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منابع مشابه

Biology and treatment of primary myelofibrosis.

Primary myelofibrosis (PMF) is a chronic myeloproliferative disorder associated with an average survival of less than 5 years. Therapy for PMF has used chemotherapeutic agents, immunomodulatory drugs, or biological-response modifiers that have not always been directed at the biological processes that underlie the origins of PMF. Such strategies are palliative and have an uncertain effect on sur...

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Treatment considerations for primary myelofibrosis.

j u l y/ a u g u s t 2 0 1 0 , v o l . 6 8 , n o 7 / 8 Primary myelofibrosis (PMF) belongs to the group of Philadelphia chromosome negative (Ph) chronic myeloproliferative neoplasms caused by a clonal stem cell disorder presenting with myeloproliferation and fibrosis. The clinical presentation is characterised by anaemia, marked hepatosplenomegaly, leuko-erythroblastosis, constitutional symptom...

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Cutaneous pathology in primary erythermalgia.

Primary or idiopathic erythermalgia is characterized by recurrent, red, warm, and painful lower extremities. It arises at young age and persists throughout life because no treatment is available. We report the cutaneous pathology of affected skin lesions of three patients with primary erythermalgia. Biopsy specimens showed a mild perivascular mononuclear infiltrate, thickened blood vessel basem...

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ژورنال

عنوان ژورنال: American Journal of Hematology

سال: 1993

ISSN: 0361-8609,1096-8652

DOI: 10.1002/ajh.2830430219